Loizeau was born in Neuilly-sur-Seine, near Paris. Her father was French, and her mother was English. Her grandmother was the acclaimed Academy Award-winning English actress Peggy Ashcroft.Around 1980, when she was five, Loizeau began to learn piano. After studying classical music for many years, she turned to studying philosophy and then theatre in London, then worked assisting composer and stage manager Georges Aperghis.Loizeau writes in many languages. She cites Georges Brassens, Bob Dylan, and The Beatles as her primary influences. Besides Bach and Franz Schubert, she also loves Renaud, and has since 1986, when she was 11 years old. She has also been influenced by Tom Waits, Nina Simone, and Randy Newman.At the end of 2001, at the age of 26, Loizeau began to perform at a small Parisian cabaret, which became for her a one-person cottage industry, printing flyers, doing publicity. She then began to collaborate with likeminded artists such as Vincent Segal, Franck Monnet, Nils Tavernier, Jean-Louis Foulquier. She signed with Fargo records at the age of 31 (their first French artist) and performed at the COmedia where she sold out for three weeks straight.